AKR7A2

Across TCGA cell cohorts, AKR7A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,076 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible AKR7A2-associated GO terms across cancer lineages are Toxin catabolic process, Mycotoxin catabolic process, and Aflatoxin catabolic process. Each is linked with AKR7A2 in more than 11 cancer types. Because this analysis shows association rather than direction, both AKR7A2-to-partner and partner-to-AKR7A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Toxin catabolic process grouped by AKR7A2-low versus AKR7A2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR7A2→partner) and Y-score (partner→AKR7A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Toxin catabolic process →	+0.195	+0.609	<.001	<.001	3	12
LIVER	Mycotoxin catabolic process →	+0.185	+0.556	<.001	.001	3	12
LIVER	Aflatoxin catabolic process →	+0.185	+0.556	<.001	.001	3	12
OESOPHAGUS	Tissue homeostasis →	-0.084	-0.736	<.001	.005	3	10
OESOPHAGUS	Anatomical structure homeostasis →	-0.084	-0.736	<.001	.005	3	10
CNS	GDP-mannose biosynthetic process →	+0.100	+0.581	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,076 associations by consensus.

Toxin catabolic process by AKR7A2 expression — LIVER

Explore this box plot interactively →