AKR1C6P

Across TCGA patient cohorts, AKR1C6P mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AKR1C6P-associated genes across cancer lineages are Endothelial cells, lymphatic Endothelial cells, and mv Endothelial cells. Each is linked with AKR1C6P in more than 1 cancer types. Because this analysis shows association rather than direction, both AKR1C6P-to-partner and partner-to-AKR1C6P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by AKR1C6P-low versus AKR1C6P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1C6P→partner) and Y-score (partner→AKR1C6P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.043	-3.416	.025	.005	3	1
UCEC	lymphatic Endothelial cells →	-0.025	-3.281	.039	.010	3	1
UCEC	mv Endothelial cells →	-0.027	-3.448	.025	.005	3	1
UCEC	Plasma cells →	-0.025	-3.416	.020	.005	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Endothelial cells by AKR1C6P expression — UCEC

Explore this box plot interactively →