AKR1B10P2

Across TCGA pan-cancer cohorts, AKR1B10P2 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated AKR1B10P2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher AKR1B10P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated AKR1B10P2 expression acts as an unfavorable survival marker.

ACC, SKCM, and PCPG are the cancer types where AKR1B10P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.164	0.835	<.001	72	view →
SKCM	DFS	Tertile	All	0.258	0.760	.004	51	view →
PCPG	DFS	Tertile	All	0.084	0.774	<.001	27	view →
ESCA	DFS	Tertile	All	0.243	0.771	.020	18	view →
UVM	OS	Tertile	All	0.249	0.712	.033	18	view →
UCEC	OS	Tertile	IV	0.231	0.592	.036	18	view →
KIRC	DFS	Tertile	All	0.268	0.633	.039	12	view →
PAAD	DFS	Tertile	II,III,IV	0.241	0.452	.049	9	view →
LIHC	OS	Tertile	III,IV	0.270	0.732	.021	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

AKR1B10P2–ACC (OS)

Open the ACC breakdown →