AKR1B10P2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, AKR1B10P2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of AKR1B10P2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where AKR1B10P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AKR1B10P2 is over-expressed in tumor.

LUSC are the cancer types where AKR1B10P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AKR1B10P2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUSCAllII,III,IV+0.017.0491view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

AKR1B10P2–LUSC

Tumor-vs-normal expression box plot for AKR1B10P2 RNA in LUSC.

Open the LUSC breakdown →

Exploration