Across TCGA patient cohorts, AKR1B10 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,634 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AKR1B10-associated proteins across cancer lineages are AKR1C3, TXNRD1, and SRXN1. Each is linked with AKR1B10 in more than 6 cancer types. Because this analysis shows association rather than direction, both AKR1B10-to-partner and partner-to-AKR1B10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B10→partner) and Y-score (partner→AKR1B10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKR1C3 →	+1.973	+3.987	<.001	<.001	3	7
LSCC	TXNRD1 →	+0.836	+3.471	<.001	<.001	3	6
LSCC	SRXN1 →	+1.651	+3.960	<.001	<.001	3	6
LSCC	GSR →	+0.624	+3.615	<.001	<.001	3	6
LSCC	G6PD →	+1.001	+4.424	<.001	<.001	3	6
LSCC	PGD →	+0.787	+4.086	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,634 associations by consensus.

Exploration

AKR1B10 survival (RNA) · tumor vs normal (RNA) · all AKR1B10 data types