Across TCGA patient cohorts, AKR1B10 protein abundance is significantly associated with the RNA expression of many other genes, with 11,837 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AKR1B10-associated genes across cancer lineages are AKR1B10P1, AKR1B15, and NMRAL2P. Each is linked with AKR1B10 in more than 5 cancer types. Because this analysis shows association rather than direction, both AKR1B10-to-partner and partner-to-AKR1B10 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B10→partner) and Y-score (partner→AKR1B10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKR1B10P1 →	+1.954	+2.392	<.001	<.001	3	6
LSCC	AKR1B15 →	+1.643	+2.249	<.001	<.001	3	6
LSCC	NMRAL2P →	+4.365	+2.627	<.001	<.001	3	6
LSCC	AKR1C3 →	+3.576	+2.604	<.001	<.001	3	6
LUAD	CYP2C18 →	+1.223	+1.915	.002	.002	3	5
GBM	ABCC3 →	+1.658	+1.262	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,837 associations by consensus.

Exploration

AKR1B10 survival (RNA) · tumor vs normal (RNA) · all AKR1B10 data types