AKNA

Across TCGA patient cohorts, AKNA protein abundance is significantly associated with the RNA expression of many other genes, with 14,439 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AKNA-associated genes across cancer lineages are TNFSF14, P2RY8, and JAK3. Each is linked with AKNA in more than 5 cancer types. Because this analysis shows association rather than direction, both AKNA-to-partner and partner-to-AKNA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKNA versus TNFSF14 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKNA→partner) and Y-score (partner→AKNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TNFSF14 →	+1.066	+0.455	<.001	<.001	3	6
LSCC	P2RY8 →	+0.933	+0.442	<.001	<.001	3	6
LSCC	JAK3 →	+0.905	+0.429	<.001	<.001	3	5
LSCC	BIN2 →	+0.872	+0.458	<.001	<.001	3	5
UCEC	ANGPTL6 →	+0.319	+0.319	.001	.001	3	5
LSCC	WAS →	+0.785	+0.351	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,439 associations by consensus.

AKNA vs TNFSF14 — UCEC

Explore this scatter interactively →