AKAP7

Across TCGA patient cohorts, AKAP7 protein abundance is significantly associated with the RNA expression of many other genes, with 7,466 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AKAP7-associated genes across cancer lineages are MEFV, STK35, and VNN2. Each is linked with AKAP7 in more than 3 cancer types. Because this analysis shows association rather than direction, both AKAP7-to-partner and partner-to-AKAP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP7 versus MEFV in COAD, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP7→partner) and Y-score (partner→AKAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MEFV →	+0.917	+1.711	.001	.002	3	4
UCEC	STK35 →	-0.443	-0.458	<.001	.001	3	4
COAD	VNN2 →	+1.279	+1.622	.001	.005	3	3
COAD	IL1B →	+1.605	+1.290	.001	<.001	3	3
COAD	FFAR2 →	+1.703	+1.873	.001	.001	3	3
COAD	FCGR3B →	+2.032	+1.541	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,466 associations by consensus.

AKAP7 vs MEFV — COAD

Explore this scatter interactively →