Across TCGA pan-cancer cohorts, AKAP17BP RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of AKAP17BP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where AKAP17BP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AKAP17BP is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

KIRC, BLCA, and THCA are the cancer types where AKAP17BP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AKAP17BP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.019	.016	5	view →
BLCA	All	All	−0.058	.013	4	view →
THCA	All	All	−0.019	.003	4	view →
READ	All	III,IV	−0.035	.019	2	view →
LIHC	All	All	+0.014	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: AKAP17BP RNA expression & survival · all AKAP17BP data types