Across TCGA patient cohorts, AKAP17A protein abundance is significantly associated with the RNA expression of many other genes, with 5,825 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible AKAP17A-associated genes across cancer lineages are GTPBP6, AHNAK, and CAVIN1. Each is linked with AKAP17A in more than 4 cancer types. Because this analysis shows association rather than direction, both AKAP17A-to-partner and partner-to-AKAP17A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP17A→partner) and Y-score (partner→AKAP17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTPBP6 →	+0.689	+0.321	<.001	<.001	3	5
LUAD	AHNAK →	-0.649	-0.214	.001	.001	3	4
BRCA	CAVIN1 →	-0.938	-0.305	<.001	<.001	3	4
HNSC	SCARNA23 →	+1.202	+0.234	<.001	.001	3	4
OV	TXLNG →	+0.563	+0.404	<.001	<.001	3	4
OV	RBBP7 →	+0.650	+0.437	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,825 associations by consensus.

Exploration

AKAP17A survival (RNA) · tumor vs normal (RNA) · all AKAP17A data types