AKAP14

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AKAP14 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AKAP14-associated genes across cancer lineages are Caspase-8 and p62 Lck ligand. Each is linked with AKAP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both AKAP14-to-partner and partner-to-AKAP14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP14→partner) and Y-score (partner→AKAP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-8 →-0.220-2.973.045.03531
UCECp62 Lck ligand →+0.286+2.331.044.01921
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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