AKAP11

Across TCGA patient cohorts, AKAP11 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,831 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AKAP11-associated proteins across cancer lineages are RPL7, GPALPP1, and ZMYM2. Each is linked with AKAP11 in more than 5 cancer types. Because this analysis shows association rather than direction, both AKAP11-to-partner and partner-to-AKAP11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP11 versus RPL7 in GBM, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP11→partner) and Y-score (partner→AKAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.406	-0.456	<.001	.001	3	6
COAD	GPALPP1 →	+0.588	+0.556	<.001	<.001	3	6
GBM	ZMYM2 →	+0.271	+0.329	.005	.007	2	6
COAD	SUCLA2 →	+0.405	+0.634	<.001	<.001	2	6
GBM	TSC22D1 →	+0.382	+0.414	<.001	<.001	3	5
GBM	KPNA3 →	+0.287	+0.430	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,831 associations by consensus.

AKAP11 vs RPL7 — GBM

Explore this scatter interactively →