AKAP10

Across TCGA patient cohorts, AKAP10 protein abundance is significantly associated with the RNA expression of many other genes, with 6,961 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AKAP10-associated genes across cancer lineages are SCO1, ATPAF2, and SMCR8. Each is linked with AKAP10 in more than 3 cancer types. Because this analysis shows association rather than direction, both AKAP10-to-partner and partner-to-AKAP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP10 versus SCO1 in BRCA, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP10→partner) and Y-score (partner→AKAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCO1 →	+0.431	+0.253	<.001	<.001	3	4
BRCA	ATPAF2 →	+0.543	+0.221	<.001	<.001	3	4
BRCA	SMCR8 →	+0.550	+0.225	<.001	<.001	3	4
BRCA	NAV3 →	+1.153	+0.197	<.001	.006	3	4
BRCA	PAFAH1B1 →	+0.424	+0.246	<.001	.001	3	4
LSCC	DERL2 →	+0.435	+0.207	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,961 associations by consensus.

AKAP10 vs SCO1 — BRCA

Explore this scatter interactively →