AKAP10

Across TCGA cell cohorts, AKAP10 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AKAP10-associated genes across cancer lineages are AVP, IL36B, and KRTAP4-1. Each is linked with AKAP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both AKAP10-to-partner and partner-to-AKAP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by AKAP10-low versus AKAP10-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP10→partner) and Y-score (partner→AKAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	IL36B →	+0.021	+5.209	.001	.005	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.151	+4.867	<.001	.009	3	1
OVARY	BPIFA3 →	+0.020	+5.807	<.001	.001	3	1
OVARY	POTED →	+0.012	+5.196	<.001	.005	3	1
LARGE_INTESTINE	ANO5 →	+0.649	+3.453	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

AVP by AKAP10 expression — BLOOD_Lymphoma

Explore this box plot interactively →