AK5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AK5 protein abundance is significantly associated with the RNA expression of many other genes, with 7,203 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AK5-associated genes across cancer lineages are CTSK, CERCAM, and TIMP3. Each is linked with AK5 in more than 3 cancer types. Because this analysis shows association rather than direction, both AK5-to-partner and partner-to-AK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK5 versus CTSK in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AK5→partner) and Y-score (partner→AK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCTSK →+1.826+0.801<.001<.00134
PDACCERCAM →+1.107+0.983<.001<.00134
OVTIMP3 →+1.451+0.765.003.00233
PDACPDGFRL →+1.230+0.832.002.00133
BRCAMEIS3 →+1.148+0.925<.001<.00133
OVPCOLCE →+0.876+0.770<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,203 associations by consensus.

AK5 vs CTSK — OV

Per-sample scatter of AK5 vs CTSK in OV (Pearson r = 0.54).

Explore this scatter interactively →

Exploration