AK5

Across TCGA cell cohorts, AK5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,009 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AK5-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Purine deoxyribonucleoside diphosphate metabolic process, and Deoxyribonucleoside diphosphate biosynthetic process. Each is linked with AK5 in more than 11 cancer types. Because this analysis shows association rather than direction, both AK5-to-partner and partner-to-AK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by AK5-low versus AK5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AK5→partner) and Y-score (partner→AK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.231	+2.812	<.001	<.001	3	12
LUNG_SCLC	Purine deoxyribonucleoside diphosphate metabolic process →	-0.254	-1.968	<.001	<.001	3	10
LIVER	Deoxyribonucleoside diphosphate biosynthetic process →	-0.218	-2.618	<.001	<.001	3	10
BONE	Positive regulation of cell-substrate junction organization →	+0.195	+2.756	<.001	<.001	3	10
LIVER	PML body organization →	+0.243	+2.361	<.001	.001	3	10
BONE	Positive regulation of stress fiber assembly →	+0.144	+2.432	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,009 associations by consensus.

Positive regulation of focal adhesion assembly by AK5 expression — BONE

Explore this box plot interactively →