AK4P3

Across TCGA patient cohorts, AK4P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,678 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AK4P3-associated GO terms across cancer lineages are Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Transcription by RNA polymerase I, and RNA localization. Each is linked with AK4P3 in more than 18 cancer types. Because this analysis shows association rather than direction, both AK4P3-to-partner and partner-to-AK4P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by AK4P3-low versus AK4P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AK4P3→partner) and Y-score (partner→AK4P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.055	+0.362	<.001	<.001	3	18
STAD	Transcription by RNA polymerase I →	+0.038	+0.297	<.001	<.001	3	18
STAD	RNA localization →	+0.055	+0.280	<.001	.006	2	19
UVM	Maturation of SSU-rRNA →	+0.048	+0.158	<.001	<.001	2	18
STAD	Protein localization to microtubule organizing center →	+0.058	+0.328	<.001	<.001	3	17
STAD	RNA capping →	+0.052	+0.325	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,678 associations by consensus.

Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by AK4P3 expression — STAD

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