AK4

Across TCGA patient cohorts, AK4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AK4-associated genes across cancer lineages are AK4P1, RPS29P7, and SH3D21. Each is linked with AK4 in more than 6 cancer types. Because this analysis shows association rather than direction, both AK4-to-partner and partner-to-AK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK4 versus AK4P1 in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AK4→partner) and Y-score (partner→AK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AK4P1 →	+0.777	+0.531	<.001	<.001	3	7
HNSC	RPS29P7 →	+1.165	+0.483	<.001	<.001	3	6
COAD	SH3D21 →	+0.850	+0.625	.001	<.001	3	5
HNSC	ACKR1 →	-1.234	-0.517	<.001	<.001	3	5
HNSC	MIR210HG →	+1.154	+0.657	<.001	<.001	3	5
HNSC	HDHD2 →	-0.364	-0.429	.008	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,886 associations by consensus.

AK4 vs AK4P1 — OV

Explore this scatter interactively →