AK2

Across TCGA patient cohorts, AK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,032 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AK2-associated proteins across cancer lineages are HAT1, FAF1, and TXLNA. Each is linked with AK2 in more than 5 cancer types. Because this analysis shows association rather than direction, both AK2-to-partner and partner-to-AK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AK2 versus HAT1 in LSCC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AK2→partner) and Y-score (partner→AK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HAT1 →	+0.388	+0.252	<.001	<.001	3	6
OV	FAF1 →	+0.391	+0.422	<.001	<.001	3	6
GBM	TXLNA →	+0.264	+0.255	.001	<.001	3	6
OV	RCC1 →	+0.407	+0.458	<.001	<.001	3	6
LSCC	DNMT1_S714 →	+0.738	+0.468	<.001	<.001	3	5
LSCC	ALDH1L2 →	-0.705	-0.394	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,032 associations by consensus.

AK2 vs HAT1 — LSCC

Explore this scatter interactively →