AIMP1

Across TCGA pan-cancer cohorts, AIMP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated AIMP1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher AIMP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated AIMP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, LSCC, and LUAD are the cancer types where AIMP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.888	.023	24	view →
LSCC	DFS	Median	III,IV	0.383	0.840	.008	19	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	14	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	9	view →
CCRCC	DFS	Tertile	IV	0.887	0.213	.024	9	view →
GBM	DFS	Quartile	All	0.640	0.947	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

AIMP1–COAD (DFS)

Open the COAD breakdown →