Across TCGA patient cohorts, AIDA protein abundance is significantly associated with the RNA expression of many other genes, with 13,120 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AIDA-associated genes across cancer lineages are OMD, LMOD1, and SYNPO2. Each is linked with AIDA in more than 7 cancer types. Because this analysis shows association rather than direction, both AIDA-to-partner and partner-to-AIDA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AIDA→partner) and Y-score (partner→AIDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OMD →	+1.283	+0.301	<.001	<.001	3	8
UCEC	LMOD1 →	+1.227	+0.269	<.001	<.001	3	8
COAD	SYNPO2 →	+1.227	+0.233	<.001	<.001	3	8
UCEC	LHFPL6 →	+0.922	+0.339	<.001	<.001	3	8
UCEC	NAP1L3 →	+1.017	+0.437	<.001	<.001	3	8
UCEC	SORBS1 →	+1.344	+0.395	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,120 associations by consensus.

Exploration

AIDA survival (RNA) · tumor vs normal (RNA) · all AIDA data types