AHSP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AHSP protein abundance is significantly associated with the RNA expression of many other genes, with 2,733 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible AHSP-associated genes across cancer lineages are HBA1, HBB, and HBA2. Each is linked with AHSP in more than 8 cancer types. Because this analysis shows association rather than direction, both AHSP-to-partner and partner-to-AHSP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AHSP versus HBA1 in GBM, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHSP→partner) and Y-score (partner→AHSP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMHBA1 →+1.724+1.032<.001<.00139
PDACHBB →+2.315+0.814<.001<.00139
OVHBA2 →+2.024+1.318<.001<.00138
CCRCCHEMGN →+0.531+0.888<.001<.00136
GBMPPBP →+1.239+0.818<.001<.00136
CCRCCSLC4A1 →+0.583+0.896.004<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,733 associations by consensus.

AHSP vs HBA1 — GBM

Per-sample scatter of AHSP vs HBA1 in GBM (Pearson r = 0.73).

Explore this scatter interactively →

Exploration