AHSP

Across TCGA cell cohorts, AHSP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,255 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AHSP-associated GO terms across cancer lineages are Positive regulation of mast cell degranulation, Response to endoplasmic reticulum stress, and Positive regulation of autophagy. Each is linked with AHSP in more than 3 cancer types. Because this analysis shows association rather than direction, both AHSP-to-partner and partner-to-AHSP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mast cell degranulation grouped by AHSP-low versus AHSP-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AHSP→partner) and Y-score (partner→AHSP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of mast cell degranulation →	+0.096	+1.378	<.001	<.001	3	4
BLOOD_Lymphoma	Response to endoplasmic reticulum stress →	+0.033	+0.498	.002	<.001	3	4
LARGE_INTESTINE	Positive regulation of autophagy →	+0.049	+0.033	<.001	.006	3	3
LARGE_INTESTINE	Positive regulation of collagen fibril organization →	-0.144	-0.023	.007	.005	3	3
LARGE_INTESTINE	Protein polyubiquitination →	+0.032	+0.024	.005	.004	3	3
LARGE_INTESTINE	DTMP catabolic process →	-0.147	-0.032	.006	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,255 associations by consensus.

Positive regulation of mast cell degranulation by AHSP expression — BLOOD_Leukemia

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