AHRR

Across TCGA patient cohorts, AHRR RNA expression is significantly associated with the go_rna of many other GO terms, with 7,100 significant associations in total. OV shows the largest number of these associations.

The most reproducible AHRR-associated GO terms across cancer lineages are RNA export from nucleus, Regulation of post-translational protein modification, and RNA secondary structure unwinding. Each is linked with AHRR in more than 26 cancer types. Because this analysis shows association rather than direction, both AHRR-to-partner and partner-to-AHRR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by AHRR-low versus AHRR-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AHRR→partner) and Y-score (partner→AHRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	RNA export from nucleus →	+0.066	+1.078	<.001	<.001	3	27
UVM	Regulation of post-translational protein modification →	+0.046	+1.058	<.001	<.001	3	27
LAML	RNA secondary structure unwinding →	+0.043	+0.464	<.001	<.001	3	27
UCS	Endosomal transport →	+0.050	+0.941	<.001	.001	3	27
UCS	Negative regulation of cell projection organization →	+0.044	+1.073	<.001	<.001	3	27
STAD	Regulation of cell morphogenesis →	+0.031	+0.324	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,100 associations by consensus.

RNA export from nucleus by AHRR expression — UVM

Explore this box plot interactively →