AHRR

Across TCGA patient cohorts, AHRR protein abundance is significantly associated with the RNA expression of many other genes, with 1,010 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AHRR-associated genes across cancer lineages are CHRDL1, CD40LG, and DNM1P46. Each is linked with AHRR in more than 1 cancer types. Because this analysis shows association rather than direction, both AHRR-to-partner and partner-to-AHRR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AHRR versus CHRDL1 in LUAD, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHRR→partner) and Y-score (partner→AHRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CHRDL1 →	+3.205	+1.949	.006	.006	3	2
LUAD	CD40LG →	+1.417	+2.167	.001	.001	3	2
LSCC	DNM1P46 →	+0.532	+1.030	.005	.005	3	2
LSCC	CENATAC-DT →	+1.029	+1.040	<.001	.006	3	2
LUAD	SETP17 →	+0.645	+1.699	.009	.002	3	2
LUAD	SEC14L3 →	+0.267	+1.840	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,010 associations by consensus.

AHRR vs CHRDL1 — LUAD

Explore this scatter interactively →