AHRR

Across TCGA patient cohorts, AHRR protein abundance is significantly associated with the protein abundance of many other proteins, with 2,100 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible AHRR-associated proteins across cancer lineages are KANK3_S177, FMO2, and ADH1B. Each is linked with AHRR in more than 1 cancer types. Because this analysis shows association rather than direction, both AHRR-to-partner and partner-to-AHRR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AHRR versus KANK3_S177 in LSCC, with a Pearson correlation of 0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AHRR→partner) and Y-score (partner→AHRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KANK3_S177 →	+0.841	+1.297	.002	<.001	3	2
LUAD	FMO2 →	+0.557	+1.462	.001	.001	3	2
LUAD	ADH1B →	+1.155	+2.176	.004	<.001	3	2
LUAD	ABI3BP →	+1.260	+2.019	.001	.005	3	1
LUAD	GPN2 →	-0.331	-1.494	.002	.001	2	2
LUAD	HACD2 →	+0.628	+1.532	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,100 associations by consensus.

AHRR vs KANK3_S177 — LSCC

Explore this scatter interactively →