AHRR

Across TCGA cell cohorts, AHRR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,619 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AHRR-associated GO terms across cancer lineages are Positive regulation of cell-substrate junction organization, Establishment of protein localization to plasma membrane, and Golgi to plasma membrane protein transport. Each is linked with AHRR in more than 10 cancer types. Because this analysis shows association rather than direction, both AHRR-to-partner and partner-to-AHRR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate junction organization grouped by AHRR-low versus AHRR-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AHRR→partner) and Y-score (partner→AHRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of cell-substrate junction organization →	+0.132	+1.906	<.001	.003	3	11
LUNG_NSCLC_LUSC	Establishment of protein localization to plasma membrane →	+0.113	+1.825	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.141	+1.788	<.001	<.001	3	10
OVARY	Vesicle cargo loading →	+0.078	+0.771	<.001	<.001	3	10
BONE	Regulation of cell-substrate junction assembly →	+0.110	+1.490	.005	.002	3	9
LUNG_NSCLC_LUSC	Regulation of angiotensin-activated signaling pathway →	+0.168	+2.138	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,619 associations by consensus.

Positive regulation of cell-substrate junction organization by AHRR expression — SOFT_TISSUE

Explore this box plot interactively →