AHR

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AHR RNA expression is significantly associated with the protein abundance of many other proteins, with 15,883 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AHR-associated proteins across cancer lineages are RAI14, CAPZA1, and CNN2. Each is linked with AHR in more than 6 cancer types. Because this analysis shows association rather than direction, both AHR-to-partner and partner-to-AHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AHR versus RAI14 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AHR→partner) and Y-score (partner→AHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRAI14 →+0.334+0.665.009.00227
PDACCAPZA1 →+0.289+0.370<.001<.00135
GBMCNN2 →+0.861+0.951<.001<.00135
OVDNAJC19 →-0.464-0.484.002.00435
GBMTLN1 →+0.437+1.246<.001<.00135
OVPALLD →+0.708+0.561.002.00735
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,883 associations by consensus.

AHR vs RAI14 — OV

Per-sample scatter of AHR vs RAI14 in OV (Pearson r = 0.40).

Explore this scatter interactively →

Exploration