Across TCGA patient cohorts, AHNAK2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,160 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AHNAK2-associated genes across cancer lineages are EMP1, IL1RN, and CD109. Each is linked with AHNAK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AHNAK2-to-partner and partner-to-AHNAK2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHNAK2→partner) and Y-score (partner→AHNAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EMP1 →	+1.210	+0.616	<.001	<.001	3	7
COAD	IL1RN →	+1.333	+0.420	<.001	.005	3	7
OV	CD109 →	+1.435	+1.000	<.001	<.001	3	7
OV	PLCD3 →	+1.103	+0.754	.003	<.001	3	7
HNSC	ANXA2 →	+0.823	+1.021	<.001	<.001	3	7
LSCC	KRT16 →	+2.481	+0.837	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,160 associations by consensus.

Exploration

AHNAK2 survival (RNA) · tumor vs normal (RNA) · all AHNAK2 data types