Across TCGA patient cohorts, AHNAK2 mutation is significantly associated with the RNA expression of many other genes, with 9,806 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AHNAK2-associated genes across cancer lineages are RAD51AP1, SKA1, and DONSON. Each is linked with AHNAK2 in more than 7 cancer types. Because this analysis shows association rather than direction, both AHNAK2-to-partner and partner-to-AHNAK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHNAK2→partner) and Y-score (partner→AHNAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RAD51AP1 →	+0.557	+1.830	<.001	<.001	3	8
STAD	SKA1 →	+0.549	+1.951	<.001	<.001	3	8
STAD	DONSON →	+0.351	+2.104	.001	.002	3	8
STAD	ORC1 →	+0.640	+1.665	<.001	<.001	3	8
STAD	EXO1 →	+0.528	+1.830	<.001	<.001	3	7
STAD	C1orf174 →	+0.326	+1.665	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,806 associations by consensus.

Exploration

AHNAK2 survival (RNA) · tumor vs normal (RNA) · all AHNAK2 data types