Across TCGA patient cohorts, AHNAK2 mutation is significantly associated with the total protein of many other genes, with 89 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AHNAK2-associated genes across cancer lineages are c-Kit, STAT3_pY705, and TFRC. Each is linked with AHNAK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AHNAK2-to-partner and partner-to-AHNAK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHNAK2→partner) and Y-score (partner→AHNAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	c-Kit →	-0.527	-2.579	.009	.011	3	7
BRCA	STAT3_pY705 →	-0.237	-1.906	.028	.017	3	5
CESC	TFRC →	+0.557	+2.584	.018	.009	3	5
STAD	ASNS →	+0.418	+1.847	<.001	.006	3	4
UCEC	4E-BP1 →	+0.255	+1.182	<.001	<.001	3	4
UCEC	Cyclin-B1 →	+0.434	+1.857	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

Exploration

AHNAK2 survival (RNA) · tumor vs normal (RNA) · all AHNAK2 data types