Across TCGA cell cohorts, AHNAK2 mutation is significantly associated with the RNA expression of many other genes, with 1,661 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AHNAK2-associated genes across cancer lineages are MROH5, H2AC21, and PROP1. Each is linked with AHNAK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both AHNAK2-to-partner and partner-to-AHNAK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHNAK2→partner) and Y-score (partner→AHNAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MROH5 →	+0.015	+3.930	<.001	.001	3	3
SKIN	H2AC21 →	+0.319	+2.327	<.001	.004	3	3
BREAST	PROP1 →	+0.062	+2.852	.008	.003	3	3
BLOOD_Leukemia	CCDC34 →	+0.821	+2.029	<.001	.002	3	3
LARGE_INTESTINE	RPAIN →	+0.576	+2.807	<.001	<.001	3	3
BLOOD_Leukemia	ORAI3 →	-1.251	-2.761	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,661 associations by consensus.

Exploration

AHNAK2 survival (RNA) · tumor vs normal (RNA) · all AHNAK2 data types