AHNAK

Across TCGA cell cohorts, AHNAK mutation is significantly associated with the RNA expression of many other genes, with 1,358 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AHNAK-associated genes across cancer lineages are TAS2R41, SUPT20HL1, and PMM1. Each is linked with AHNAK in more than 3 cancer types. Because this analysis shows association rather than direction, both AHNAK-to-partner and partner-to-AHNAK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R41 grouped by AHNAK-low versus AHNAK-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHNAK→partner) and Y-score (partner→AHNAK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	TAS2R41 →	+0.019	+2.158	<.001	.006	3	3
LUNG_SCLC	SUPT20HL1 →	+0.014	+2.647	.001	.003	3	3
BLOOD_Leukemia	PMM1 →	+0.717	+2.518	<.001	.003	3	3
LARGE_INTESTINE	ELP3 →	+0.531	+2.672	.001	<.001	3	3
BLOOD_Leukemia	GPR63 →	+0.830	+2.532	.001	<.001	3	3
BLOOD_Leukemia	MEAK7 →	+0.568	+3.518	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,358 associations by consensus.

TAS2R41 by AHNAK expression — OVARY

Explore this box plot interactively →