AHCYL1

Across TCGA cell cohorts, AHCYL1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible AHCYL1-associated genes across cancer lineages are FSHB, LEUTX, and MTRNR2L10. Each is linked with AHCYL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AHCYL1-to-partner and partner-to-AHCYL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FSHB grouped by AHCYL1-low versus AHCYL1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHCYL1→partner) and Y-score (partner→AHCYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FSHB →	+0.018	+4.321	<.001	.009	3	1
CNS	LEUTX →	+0.168	+4.321	<.001	.009	3	1
CNS	MTRNR2L10 →	+0.012	+5.357	<.001	.001	3	1
BLOOD_Leukemia	IQCF5 →	+0.124	+5.201	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR2L8 →	+0.020	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FSHB by AHCYL1 expression — CNS

Explore this box plot interactively →