AGTPBP1

Across TCGA pan-cancer cohorts, AGTPBP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated AGTPBP1 data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher AGTPBP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated AGTPBP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

HNSC, PDAC, and LSCC are the cancer types where AGTPBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.960	0.736	<.001	84	view →
PDAC	OS	Quartile	II,III,IV	1.000	0.793	.006	13	view →
LSCC	DFS	Tertile	All	0.815	0.331	.031	5	view →
CCRCC	DFS	Tertile	IV	1.000	0.150	.024	4	view →
UCEC	DFS	Median	II,III,IV	0.867	0.534	.044	4	view →
LUAD	OS	Median	II,III,IV	0.895	0.964	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

AGTPBP1–HNSC (OS)

Open the HNSC breakdown →