AGTPBP1

Across TCGA pan-cancer cohorts, AGTPBP1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of AGTPBP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where AGTPBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AGTPBP1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

COAD, LUAD, and THCA are the cancer types where AGTPBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AGTPBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	+0.791	<.001	10	view →
LUAD	Female	III,IV	−1.493	<.001	9	view →
THCA	All	II,III,IV	−0.473	<.001	8	view →
KICH	Female	All	−1.454	<.001	7	view →
LIHC	Female	All	+0.564	<.001	7	view →
LUSC	Female	II,III,IV	−1.325	<.001	6	view →
READ	Male	All	+0.799	<.001	6	view →
STAD	All	II,III,IV	+0.659	<.001	6	view →
BRCA	Female	All	−0.272	<.001	6	view →
CHOL	All	All	+1.400	<.001	5	view →
HNSC	All	III,IV	+0.473	.006	5	view →
UCEC	All	II,III,IV	+0.992	.004	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

AGTPBP1–COAD

Open the COAD breakdown →