AGTPBP1

Across TCGA patient cohorts, AGTPBP1 mutation is significantly associated with the RNA expression of many other genes, with 3,655 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGTPBP1-associated genes across cancer lineages are UQCRC1, POLR3H, and TPI1. Each is linked with AGTPBP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AGTPBP1-to-partner and partner-to-AGTPBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UQCRC1 grouped by AGTPBP1-low versus AGTPBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGTPBP1→partner) and Y-score (partner→AGTPBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UQCRC1 →	+0.393	+2.211	<.001	<.001	3	4
UCEC	POLR3H →	+0.424	+2.436	<.001	<.001	3	3
UCEC	TPI1 →	+0.420	+2.146	.001	<.001	3	3
UCEC	NDUFS7 →	+0.530	+2.157	<.001	<.001	3	3
UCEC	DDX54 →	+0.424	+1.928	<.001	<.001	3	3
UCEC	DDA1 →	+0.286	+1.928	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,655 associations by consensus.

UQCRC1 by AGTPBP1 expression — UCEC

Explore this box plot interactively →