AGTPBP1

Across TCGA patient cohorts, AGTPBP1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGTPBP1-associated genes across cancer lineages are Caspase-7-cleavedD198, ERK2, and TFRC. Each is linked with AGTPBP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AGTPBP1-to-partner and partner-to-AGTPBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by AGTPBP1-low versus AGTPBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGTPBP1→partner) and Y-score (partner→AGTPBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.682	+2.756	<.001	<.001	3	3
UCEC	ERK2 →	+0.144	+1.807	.017	.024	3	2
UCEC	TFRC →	+0.466	+1.584	.005	.005	3	2
UCEC	ASNS →	+0.296	+1.700	.009	.040	3	2
UCEC	c-Kit →	-0.170	-1.584	.020	.005	3	2
UCEC	4E-BP1 →	+0.303	+3.700	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Caspase-7-cleavedD198 by AGTPBP1 expression — UCEC

Explore this box plot interactively →