AGPS

Across TCGA cell cohorts, AGPS mutation is significantly associated with the drug of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AGPS-associated genes across cancer lineages are OF-1, WYE-125132, and GSK2256098C. Each is linked with AGPS in more than 1 cancer types. Because this analysis shows association rather than direction, both AGPS-to-partner and partner-to-AGPS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OF-1 grouped by AGPS-low versus AGPS-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPS→partner) and Y-score (partner→AGPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OF-1 →	+0.356	+2.646	.013	.047	3	1
LARGE_INTESTINE	WYE-125132 →	+0.625	+2.652	.013	.045	3	1
LARGE_INTESTINE	GSK2256098C →	+0.308	+2.906	.046	.033	1	1
LARGE_INTESTINE	AT7867 →	+0.522	+2.652	.030	.045	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OF-1 by AGPS expression — LARGE_INTESTINE

Explore this box plot interactively →