AGPAT4

Across TCGA patient cohorts, AGPAT4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,625 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AGPAT4-associated genes across cancer lineages are LGALS1, ARSI, and FAM131B. Each is linked with AGPAT4 in more than 4 cancer types. Because this analysis shows association rather than direction, both AGPAT4-to-partner and partner-to-AGPAT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGPAT4 versus LGALS1 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPAT4→partner) and Y-score (partner→AGPAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LGALS1 →	+0.907	+0.480	<.001	<.001	3	5
LSCC	ARSI →	+0.987	+0.449	<.001	<.001	3	5
GBM	FAM131B →	+1.049	+0.321	<.001	<.001	3	4
OV	PDPN →	+1.239	+0.518	.001	<.001	3	4
BRCA	RASA3 →	+0.680	+0.383	.003	.005	3	4
HNSC	LINC01615 →	+0.770	+0.480	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,625 associations by consensus.

AGPAT4 vs LGALS1 — BRCA

Explore this scatter interactively →