AGPAT4

Across TCGA cell cohorts, AGPAT4 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible AGPAT4-associated genes across cancer lineages are TCP11X2, PABPN1L, and PF4V1. Each is linked with AGPAT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGPAT4-to-partner and partner-to-AGPAT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCP11X2 grouped by AGPAT4-low versus AGPAT4-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPAT4→partner) and Y-score (partner→AGPAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TCP11X2 →	+0.123	+5.087	<.001	.004	3	1
LARGE_INTESTINE	PABPN1L →	+0.034	+4.054	.003	.004	3	1
STOMACH	PF4V1 →	+0.564	+3.432	<.001	.008	3	1
STOMACH	MRGPRX1 →	+0.280	+4.044	<.001	.003	3	1
STOMACH	MS4A12 →	+0.024	+4.247	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TCP11X2 by AGPAT4 expression — URINARY_TRACT

Explore this box plot interactively →