AGPAT3

Across TCGA patient cohorts, AGPAT3 mutation is significantly associated with the RNA expression of many other genes, with 3,293 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGPAT3-associated genes across cancer lineages are RNA5SP412, RNU6-206P, and IGHD3-22. Each is linked with AGPAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGPAT3-to-partner and partner-to-AGPAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by AGPAT3-low versus AGPAT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPAT3→partner) and Y-score (partner→AGPAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.531	+1.829	<.001	.001	3	2
UCEC	RNU6-206P →	+0.084	+2.972	.003	.005	3	2
COAD	IGHD3-22 →	+2.051	+3.716	.004	.006	3	2
UCEC	RNA5SP423 →	+0.578	+1.580	<.001	.004	3	2
UCEC	RNA5SP415 →	+0.506	+2.135	<.001	<.001	3	2
BLCA	OR51A8P →	+0.039	+4.433	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,293 associations by consensus.

RNA5SP412 by AGPAT3 expression — UCEC

Explore this box plot interactively →