Across TCGA patient cohorts, AGPAT1 mutation is significantly associated with the RNA expression of many other genes, with 1,517 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGPAT1-associated genes across cancer lineages are COPS8P1, MIR6766, and SSXP4. Each is linked with AGPAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AGPAT1-to-partner and partner-to-AGPAT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPAT1→partner) and Y-score (partner→AGPAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	COPS8P1 →	+0.050	+5.355	.004	.005	3	3
UCEC	MIR6766 →	+0.321	+3.037	<.001	.002	3	3
LUAD	SSXP4 →	+0.060	+5.117	<.001	.001	3	2
LUAD	RNA5SP231 →	+0.225	+4.526	<.001	.004	3	2
UCEC	TONSL →	+0.684	+2.606	.005	.006	3	2
UCEC	RNA5SP417 →	+0.705	+2.936	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,517 associations by consensus.

Exploration

AGPAT1 survival (RNA) · tumor vs normal (RNA) · all AGPAT1 data types