AGO3

Across TCGA patient cohorts, AGO3 RNA expression is significantly associated with the RNA expression of many other genes, with 21,751 significant associations in total. UVM shows the largest number of these associations.

The most reproducible AGO3-associated genes across cancer lineages are DYRK2, HP1BP3, and AKAP9. Each is linked with AGO3 in more than 33 cancer types. Because this analysis shows association rather than direction, both AGO3-to-partner and partner-to-AGO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGO3 versus DYRK2 in UVM, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGO3→partner) and Y-score (partner→AGO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	DYRK2 →	+1.183	+0.849	<.001	<.001	3	34
UVM	HP1BP3 →	+1.378	+0.938	<.001	<.001	3	34
UVM	AKAP9 →	+1.757	+0.874	<.001	<.001	3	34
DLBC	LATS1 →	+1.402	+0.946	<.001	<.001	3	34
DLBC	ANKRD17 →	+1.805	+0.996	<.001	<.001	3	34
DLBC	VHL →	+1.440	+0.865	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,751 associations by consensus.

AGO3 vs DYRK2 — UVM

Explore this scatter interactively →