AGMAT

Across TCGA patient cohorts, AGMAT mutation is significantly associated with the RNA expression of many other genes, with 413 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGMAT-associated genes across cancer lineages are APOOP3, RNA5SP507, and RPL31P13. Each is linked with AGMAT in more than 2 cancer types. Because this analysis shows association rather than direction, both AGMAT-to-partner and partner-to-AGMAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APOOP3 grouped by AGMAT-low versus AGMAT-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGMAT→partner) and Y-score (partner→AGMAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	APOOP3 →	+0.043	+3.990	<.001	.009	3	3
SKCM	RNA5SP507 →	+0.553	+3.215	<.001	.002	3	2
SKCM	RPL31P13 →	+0.076	+3.362	<.001	.006	3	2
COAD	PFN1P10 →	+0.226	+4.271	<.001	.003	3	2
UCEC	SEC13 →	+0.429	+3.584	.006	.003	3	2
UCEC	CENPW →	+0.941	+3.191	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 413 associations by consensus.

APOOP3 by AGMAT expression — SKCM

Explore this box plot interactively →