AGK

Across TCGA patient cohorts, AGK protein abundance is significantly associated with the RNA expression of many other genes, with 19,400 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AGK-associated genes across cancer lineages are REPIN1, MKRN1, and MRPS33. Each is linked with AGK in more than 5 cancer types. Because this analysis shows association rather than direction, both AGK-to-partner and partner-to-AGK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGK versus REPIN1 in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGK→partner) and Y-score (partner→AGK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	REPIN1 →	+0.854	+0.275	<.001	.003	3	6
LSCC	MKRN1 →	+0.549	+0.353	<.001	<.001	3	6
LSCC	MRPS33 →	+0.577	+0.343	<.001	<.001	3	6
UCEC	ACTR3B →	+0.449	+0.420	<.001	<.001	3	5
UCEC	COLEC12 →	-0.831	-0.399	<.001	<.001	3	5
COAD	VGLL3 →	-0.847	-0.246	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,400 associations by consensus.

AGK vs REPIN1 — HNSC

Explore this scatter interactively →