AGFG1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AGFG1 mutation is significantly associated with the RNA expression of many other genes, with 2,732 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGFG1-associated genes across cancer lineages are CD24P1, OFD1P16Y, and EML2-AS1. Each is linked with AGFG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AGFG1-to-partner and partner-to-AGFG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD24P1 grouped by AGFG1-low versus AGFG1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGFG1→partner) and Y-score (partner→AGFG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCD24P1 →+0.173+3.942.001.00233
BRCAOFD1P16Y →+0.129+9.057<.001.00332
COADEML2-AS1 →+0.085+3.063<.001.00832
UCECSNX3P1Y →+0.062+3.777<.001.00732
UCECAQP7P4 →+0.027+2.442.002.00632
LUSCTUBB8P3 →+0.081+5.031.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,732 associations by consensus.

CD24P1 by AGFG1 expression — COAD

Box plot of CD24P1 in AGFG1-low vs AGFG1-high samples in COAD.

Explore this box plot interactively →

Exploration