AGFG1

Across TCGA pan-cancer cohorts, AGFG1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated AGFG1 data layer compared with 5 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher AGFG1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated AGFG1 expression acts as an unfavorable survival marker, although some lineages such as UCS and COAD show a favorable association.

ACC, CESC, and LIHC are the cancer types where AGFG1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.222	0.679	<.001	116	view →
CESC	DFS	Median	All	0.637	0.848	<.001	102	view →
LIHC	DFS	Median	All	0.451	0.634	<.001	95	view →
UVM	DFS	Quartile	All	0.283	0.825	.001	79	view →
BLCA	OS	Tertile	II,III,IV	0.540	0.693	.003	49	view →
OV	OS	Quartile	III,IV	0.244	0.404	<.001	46	view →
LUAD	OS	Median	All	0.259	0.420	<.001	45	view →
UCEC	DFS	Quartile	All	0.782	0.910	<.001	24	view →
UCS	DFS	Tertile	IV	0.942	0.403	.024	24	view →
LGG	OS	Median	All	0.350	0.591	<.001	22	view →
COAD	OS	Median	All	0.857	0.748	.003	16	view →
HNSC	OS	Median	All	0.629	0.784	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

AGFG1–ACC (DFS)

Open the ACC breakdown →