Across TCGA patient cohorts, AGER RNA expression is significantly associated with the protein abundance of many other proteins, with 14,438 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AGER-associated proteins across cancer lineages are SIN3A, PHF1, and TNS2. Each is linked with AGER in more than 4 cancer types. Because this analysis shows association rather than direction, both AGER-to-partner and partner-to-AGER results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGER→partner) and Y-score (partner→AGER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIN3A →	+0.195	+0.276	.003	.001	3	5
GBM	PHF1 →	+0.214	+0.385	.002	.001	3	4
CCRCC	TNS2 →	+0.342	+0.465	.003	<.001	3	4
CCRCC	TNS2_S931 →	+0.588	+0.336	.001	.004	3	4
CCRCC	PPP1R12B →	+0.546	+0.283	.002	.002	3	4
HNSC	SMC3 →	+0.248	+0.620	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,438 associations by consensus.

Exploration

AGER survival (RNA) · tumor vs normal (RNA) · all AGER data types