AGBL1

Across TCGA patient cohorts, AGBL1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible AGBL1-associated genes across cancer lineages are CXorf66. Each is linked with AGBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGBL1-to-partner and partner-to-AGBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXorf66 grouped by AGBL1-low versus AGBL1-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGBL1→partner) and Y-score (partner→AGBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	CXorf66 →	+0.141	+5.624	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CXorf66 by AGBL1 expression — SCLC

Explore this box plot interactively →